Search by BoMiProt ID - Bomi615


Primary Information

BoMiProt ID Bomi615
Protein Name Beta-arrestin-1
Organism Bos taurus
Uniprot IDP17870
Milk FractionExosome
Ref Sequence ID NP_776668.1
Aminoacid Length 418
Molecular Weight 47132
FASTA Sequence Download
Gene Name ARRB1
Gene ID 281637
Protein Existence Status Reveiwed:Experimental evidence at protein level

Secondary Information

PTMs Phosphorylation at Serine
Significance of PTMs G-protein-coupled receptor kinases (GRK) regulate the function of beta-adrenergic receptors through rapid phosphorylation only to activated receptors, leading to a process termed homologous desensitization.
Linking IDs Bomi615
Bibliography 1. Lefkowitz RJ. G protein-coupled receptor kinases. Cell 1993; 74:409–412.
PTMs Phosphorylation at Serine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions 1-10,90-94,176-187,353-383,391-418
DisProt Annotation Disorder content 9.3%
Term small molecule binding, Fragment 383 - 393
Term molecular adaptor activity, Fragment 383 - 393
Term small molecule binding, Fragment 282 - 309
Term molecular adaptor activity, Fragment 282 - 309
TM Helix Prediction No TM helices
Significance of PTMs G-protein-coupled receptor kinases (GRK) regulate the function of beta-adrenergic receptors through rapid phosphorylation only to activated receptors, leading to a process termed homologous desensitization.
Linking IDs
Bibliography 1. Lefkowitz RJ. G protein-coupled receptor kinases. Cell 1993; 74:409–412.