Primary Information |
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| BoMiProt ID | Bomi10637 |
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| Protein Name | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1/RPGR-interacting protein 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q9GLM3 |
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| Milk Fraction | whey |
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| Ref Sequence ID | NP_851377.1 |
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| Aminoacid Length | 1221 |
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| Molecular Weight | 138434 |
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| FASTA Sequence |
Download |
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| Gene Name | RPGRIP1 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | Retina, brain, skeletal muscle and kidney |
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| Protein Function | May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells |
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| Linking IDs | Bomi10637 |
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| Bibliography | Roepman, R., Bernoud-Hubac, N., Schick, D. E., Maugeri, A., Berger, W., Ropers, H. H., Cremers, F. P., & Ferreira, P. A. (2000). The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors. Human molecular genetics, 9(14), 2095–2105. https://doi.org/10.1093/hmg/9.14.2095 |
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| Presence in other biological fluids/tissue/cells | Retina, brain, skeletal muscle and kidney |
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| Protein Function | May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 1-5, 88-107, 860-910, 1014-1032 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Linking IDs | |
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| Bibliography | Roepman, R., Bernoud-Hubac, N., Schick, D. E., Maugeri, A., Berger, W., Ropers, H. H., Cremers, F. P., & Ferreira, P. A. (2000). The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors. Human molecular genetics, 9(14), 2095–2105. https://doi.org/10.1093/hmg/9.14.2095 |
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