Primary Information
BoMiProt ID	Bomi9992
Protein Name	Transmembrane protein 108/Retrolinkin
Organism	Bos taurus
Uniprot ID	A6QLF8
Milk Fraction	Whey
Ref Sequence ID	NP_001095409.1
Aminoacid Length	583
Molecular Weight	60785
FASTA Sequence	Download
Gene Name	TMEM108
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons.
PTMs	Glycosylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	77-94, 116-155, 158-217, 261-419, 443-461, 547-555
DisProt Annotation
TM Helix Prediction	2TMHs ; (7-29) , (477-499)
Bibliography	Jiao, H. F., Sun, X. D., Bates, R., Xiong, L., Zhang, L., Liu, F., Li, L., Zhang, H. S., Wang, S. Q., Xiong, M. T., Patel, M., Stranahan, A. M., Xiong, W. C., Li, B. M., & Mei, L. (2017). Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America, 114(5), 1177–1182. https://doi.org/10.1073/pnas.1618213114