Primary Information |
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| BoMiProt ID | Bomi9933 |
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| Protein Name | Transcription factor Dp-1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q17QZ4 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001069497.1 |
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| Aminoacid Length | 410 |
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| Molecular Weight | 44926 |
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| FASTA Sequence |
Download |
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| Gene Name | TFDP1 |
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| Gene ID | 534579 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | regulate the cell cycle during the G1 to S phase transition via transcriptional regulation of target genes. |
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| Biochemical Properties | comprises three DP subunits (DP-1 to DP-3) and eight E2F subunits (E2F-1 to E2F-8).The region important for protein stabilization may reside in the C-terminus of DP-1. |
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| PTMs | Acetylation, Phosphorylation, Ubl conjugation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q17QZ4|TFDP1_BOVIN Transcription factor Dp-1 OS=Bos taurus OX=9913 GN=TFDP1 PE=2 SV=1
MAKDAGLIEANGELKVFIDQNLS*23PGKGVVSLVAVHPSTVNSLGKQLLPKTFGQSNVNITQ
QVVIGTPQRPAAPNTIVVGSPHTPNTHFVSQNQPSDPSPWSAGKRNRKGEKNGKGLRHFS
MKVCEKVQRKGTTSYNEVADELVAEFSAADSHILPSESAYDQKNIRRRVYDALNVLMAMN
IISKEKKEIKWIGLPTNSAQECQSLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRN
RQVEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVL
KRMGMACGLESGSCSPEDLRVARSLVPKALEPYVTEMAQGSLGGVFVASAVSTSNGTRLS
ASDLANGADGALATSSSGSQYSGSRVETPVSCVGEDDEDDEDFNENEEED
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| Predicted Disorder Regions | 66-74, 83-124, 241-253, 342-345, 354-410 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Arakawa T, Masuhiro Y, Kamiya Y, Kojima H, Hanazawa S. Identification of significant regions of transcription factor DP-1 (TFDP-1) involved in stability/instability of the protein. Biochem Biophys Res Commun. 2010 Jun 25;397(2):345-9. doi: 10.1016/j.bbrc.2010.05.127. Epub 2010 May 27. PMID: 20513349. |
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