Primary Information |
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| BoMiProt ID | Bomi9819 |
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| Protein Name | Thrombospondin-2/Corticotropin-induced secreted protein |
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| Organism | Bos taurus |
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| Uniprot ID | Q95116 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_789861.1 |
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| Aminoacid Length | 1170 |
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| Molecular Weight | 129863 |
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| FASTA Sequence |
Download |
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| Gene Name | THBS2/TSP-2/TSP2 |
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| Gene ID | 338092 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.modulates collagen fibrillogenesis and angiogenesis |
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| PTMs | Disulfide bond, Glycosylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q95116|TSP2_BOVIN Thrombospondin-2 OS=Bos taurus OX=9913 GN=THBS2 PE=2 SV=2
MLWPLLLLALWAWPSAQAGDQDEDTAFDLFSISNINRKTIGAKQFRGPDPSVPAYRFVRF
DYIPPVSAEHLGRITEAMRRKEGFFLTASMKQDRRSRGTLLALEGPGATHRQFEIVSNGP
ADTLDLTYWVDGTQHVISLEDVGLADSQWKN*151VTVQVTGETYSLYVGCDLMDSFALDEPFY
EHLQTERSRMYVTKGAARESHFRGLLQNVYLVFENSVEDLLSKKGCQQSQGAETNAISEN
TETLHLSPMVTMEHVGPSAEKSPEVCEHSCEELGSMIRELSGLHVIVNQLHENLRKVSND
NQFLWELIGGPPKTRN*316VSACWQDGRFFAEN*330ETWVVDSCTKCTCKKFKTVCHQISCPPATC
ADPWFVEGECCPSCVHDGEEGWSPWAEWTECSATCGSGTQQRGRSCDVTSNTCLGPSIQT
RACSLGRCDHRIRQDGGWSHWSPWSSCSVTCGVGN*455VTRIRLCNSPVPQMGGRSCKGSGRE
TKACQGPPCPVDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQHGGKDCVGGAKEQQM
CNRKSCPIDGCLSNPCFPGAECSSFPDGSWSCGSCPGGFLGN*582GTHCEDLDECAVVTDVCF
ATSKAHRCVNTNPGYHCLPCPPRYKGNQPFGVGLEAARTEKQVCEPENPCKDKTHSCHRH
AECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNKNLVCATN*708ATYHCVKDNCPL
LPNSGQEDFDKDGIGDACDDDDDNDGVSDEKDNCQLLFNPRQFDYDKDEVGDRCDNCPYV
HNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVH
NPDQTDVDNDLVGDQCDNNEDIDEDGHQNNQDNCPHIPNANQADHDRDGQGDACDSDDDN
DGIPDDRDNCRLVANPDQEDSDGDRRGDACKDDFDN*936DSIPDIDDVCPENNAISETDFRNF
QMVHLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDD
DYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVN*1067STTGTGEHLRNAL
WHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYD
QTYAGGRLGLFVFSQEMVYFSDLKYECRDV
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| Predicted Disorder Regions | 766-974 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Bornstein P, Kyriakides TR, Yang Z, Armstrong LC, Birk DE. Thrombospondin 2 modulates collagen fibrillogenesis and angiogenesis. J Investig Dermatol Symp Proc. 2000 Dec;5(1):61-6. doi: 10.1046/j.1087-0024.2000.00005.x. PMID: 11147677. 2.Lawler J. The functions of thrombospondin-1 and-2. Curr Opin Cell Biol. 2000 Oct;12(5):634-40. doi: 10.1016/s0955-0674(00)00143-5. PMID: 10978901. |
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