Primary Information |
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| BoMiProt ID | Bomi9810 |
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| Protein Name | Thioredoxin, mitochondrial/MTRX/Mt-Trx/Thioredoxin-2 |
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| Organism | Bos taurus |
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| Uniprot ID | Q95108 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_776633.1 |
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| Aminoacid Length | 166 |
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| Molecular Weight | 18416 |
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| FASTA Sequence |
Download |
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| Gene Name | TXN2 |
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| Gene ID | 281557 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | antioxidant system in defense against oxidative stress through its disulfide reductase activity regulating protein dithiol/disulfide balance. |
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| PTMs | Acetylation,Disulfide bond |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Significance of PTMs | cysteine 73, glutathionylated cysteines in plant thioredoxin are located in the flexible α3– β4 loop.Both in mammals and plants,Glutathionylation of thioredoxin led to a reduction in the enzymatic activity of thioredoxin under conditions of oxidative stress. |
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