Search by BoMiProt ID - Bomi9597

Primary Information

BoMiProt ID Bomi9597
Protein Name Suppressor of tumorigenicity 7 protein-like
Organism Bos taurus
Uniprot IDA3KN28
Milk FractionWhey
Ref Sequence ID NP_001076950.1
Aminoacid Length 555
Molecular Weight 62636
FASTA Sequence Download
Gene Name ST7L
Gene ID 534657
Protein Existence Status reviewed

Secondary Information

Protein Function Tumour supressor protein.found to decrease glycogen synthase kinase (GSK)-3β phosphorylation and downregulate active β-catenin protein expression, thereby leading to repression of β-catenin transcriptional activity.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 9-15, 126-147, 272-280
DisProt Annotation
TM Helix Prediction 2TMHs; (38-60) and (80-102)
Bibliography Wang H, Sun L, Jiang J, Yu S, Zhou Q. Suppression of the proliferation and invasion of breast cancer cells by ST7L occurs through inhibition of activation of Wnt/GSK-3β/β-catenin signalling. Clin Exp Pharmacol Physiol. 2020 Jan;47(1):119-126. doi: 10.1111/1440-1681.13166. Epub 2019 Sep 9. PMID: 31429477.