Search by BoMiProt ID - Bomi9566

Primary Information

BoMiProt ID Bomi9566
Protein Name Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial/SCS-alpha/Succinyl-CoA synthetase subunit alpha
Organism Bos taurus
Uniprot IDQ58DR8
Milk FractionWhey
Ref Sequence ID NP_001030254.1
Aminoacid Length 346
Molecular Weight 36167
FASTA Sequence Download
Gene Name SUCLG1
Gene ID 509983
Protein Existence Status reviewed

Secondary Information

Protein Function Succinyl-CoA synthetase participates in the citric acid cycle (TCA) , the hydrolysis of succinyl-CoA to the synthesize either ATP or GTP and succinate.maintenance of mitochondrial DNA (mtDNA)
PTMs Acetylation on Lys
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction no TM helices
Additional Comments mtDNA depletion and Encephalomyopathy due to mutation of this gene
Bibliography El-Hattab AW, Scaglia F. SUCLG1-Related Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form with Methylmalonic Aciduria. 2017 Mar 30. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Mirzaa GM, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2021. PMID: 28358460.