Primary Information
BoMiProt ID	Bomi9566
Protein Name	Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial/SCS-alpha/Succinyl-CoA synthetase subunit alpha
Organism	Bos taurus
Uniprot ID	Q58DR8
Milk Fraction	Whey
Ref Sequence ID	NP_001030254.1
Aminoacid Length	346
Molecular Weight	36167
FASTA Sequence	Download
Gene Name	SUCLG1
Gene ID	509983
Protein Existence Status	reviewed
Secondary Information
Protein Function	Succinyl-CoA synthetase participates in the citric acid cycle (TCA) , the hydrolysis of succinyl-CoA to the synthesize either ATP or GTP and succinate.maintenance of mitochondrial DNA (mtDNA)
PTMs	Acetylation on Lys
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	no TM helices
Additional Comments	mtDNA depletion and Encephalomyopathy due to mutation of this gene
Bibliography	El-Hattab AW, Scaglia F. SUCLG1-Related Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form with Methylmalonic Aciduria. 2017 Mar 30. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Mirzaa GM, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2021. PMID: 28358460.