Search by BoMiProt ID - Bomi9349

Primary Information

BoMiProt ID Bomi9349
Protein Name Solute carrier family 35 member B1/Endoplasmic reticulum nucleotide sugar transporter 1
Organism Bos taurus
Uniprot IDQ8MII5
Milk FractionWhey
Ref Sequence ID NP_851934.1
Aminoacid Length 322
Molecular Weight 35703
FASTA Sequence Download
Gene Name SLC35B1/ERNST
Gene ID 353217
Protein Existence Status reviewed

Secondary Information

Protein Function  SLC35B1 operates as an ATP/ADP exchanger in the ER membrane. ten transmembrane helices
Significance in milk lactose synthesis
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 1-5, 133-139, 313-322
DisProt Annotation
TM Helix Prediction 7TMHs; (12-30),(49-71),(84-106),(136-154),(206-224), (243-265), (278-300)
Bibliography Klein MC, Zimmermann K, Schorr S, Landini M, Klemens PAW, Altensell J, Jung M, Krause E, Nguyen D, Helms V, Rettig J, Fecher-Trost C, Cavalié A, Hoth M, Bogeski I, Neuhaus HE, Zimmermann R, Lang S, Haferkamp I. AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum. Nat Commun. 2018 Aug 28;9(1):3489. doi: 10.1038/s41467-018-06003-9. PMID: 30154480; PMCID: PMC6113206.