Primary Information |
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BoMiProt ID | Bomi9320 |
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Protein Name | Solute carrier family 22 member 7/Organic anion transporter 2 |
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Organism | Bos taurus |
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Uniprot ID | A6QLW8 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_001094517.1 |
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Aminoacid Length | 547 |
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Molecular Weight | 60004 |
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FASTA Sequence |
Download |
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Gene Name | SLC22A7/OAT2 |
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Gene ID | 407224 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | Mediates sodium-independent multispecific organic anion transport.facilitative transporter for cGMP and other guanine nucleotides.Nicotinic acid transport in human liver. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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Predicted Disorder Regions | 91-120, 524-547 |
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DisProt Annotation | |
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TM Helix Prediction | 11TMHs; (22-44), (146-164), (173-195), (202-220), (229-251), (258-276), (342-360), (367-385), (404-422), (429-451), (489-511) |
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Bibliography | Mathialagan S, Bi YA, Costales C, Kalgutkar AS, Rodrigues AD, Varma MVS. Nicotinic acid transport into human liver involves organic anion transporter 2 (SLC22A7). Biochem Pharmacol. 2020 Apr;174:113829. doi: 10.1016/j.bcp.2020.113829. Epub 2020 Jan 28. PMID: 32001236. |