Primary Information |
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| BoMiProt ID | Bomi9278 |
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| Protein Name | Sodium/hydrogen exchanger 1/Na(+)/H(+) exchanger 1/Solute carrier family 9 member 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q28036 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_777258.1 |
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| Aminoacid Length | 817 |
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| Molecular Weight | 91017 |
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| FASTA Sequence |
Download |
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| Gene Name | SLC9A1/NHE1 |
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| Gene ID | 317654 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | plays an essential role in maintaining intracellular pH (pHi) homeostasis |
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| PTMs | Glycosylation, Phosphorylation, Ubl conjugation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q28036|SL9A1_BOVIN Sodium/hydrogen exchanger 1 OS=Bos taurus OX=9913 GN=SLC9A1 PE=2 SV=1
MLLWPGASGLPPPRIFPSLLVVVALVGLLPVLRSYGLQISPTASTIRGSEPPRERSIGDV
TTAPPELAPESRPVN*75HSFAEHSPKARKAFPVLGIDYQHVRIPFEIALWILLACLMKIGFH
VIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPILQSEVFFLFLLPPIILDAGYFLPLR
QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLENLLFGSIISAVDPV
AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYDRVGIVDIILGFLSFFV
VSLGGVFVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG
VVMRPYVEAN*370ISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF
CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLF
LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH
YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPS*599A
VS*602T*603VS*605MQNIHPKSLPAERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE
EAWNQMLLRRQKARQLEQKISNYLTVPAHKLDS*693PTMS*697RARIGS*703DPLAYEPKADLPVITID
PAS*723PQS*726PES*729VDLVNEELKGKVLGLSRDPGRLAEEEEDDNGPRWLTMRTKEPSSPGTDDVF
TPAPSDS*787PSSQRIQRCLS*798DPGPHPEPGEGEPFIPKGQ |
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| Predicted Disorder Regions | 48-83, 687-817 |
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| DisProt Annotation | |
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| TM Helix Prediction | 12TMHs; (15-37), (106-124), (128-146), (159-177), (189-211), (224-246), (255-277), (298-320), (339-361), (382-404), (413-435), (479-497) |
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| Bibliography | Song H, Yuan S, Zhang Z, Zhang J, Zhang P, Cao J, Li H, Li X, Shen H, Wang Z, Chen G. Sodium/Hydrogen Exchanger 1 Participates in Early Brain Injury after Subarachnoid Hemorrhage both in vivo and in vitro via Promoting Neuronal Apoptosis. Cell Transplant. 2019 Aug;28(8):985-1001. doi: 10.1177/0963689719834873. Epub 2019 Mar 6. PMID: 30838887; PMCID: PMC6728713. |
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