Primary Information
BoMiProt ID	Bomi9251
Protein Name	S-methyl-5'-thioadenosine phosphorylase/5'-methylthioadenosine phosphorylase
Organism	Bos taurus
Uniprot ID	Q3MHF7
Milk Fraction	Exosomes,MFGM
Ref Sequence ID	XP_002689552.1
Aminoacid Length	283
Molecular Weight	31256
FASTA Sequence	Download
Gene Name	MTAP
Gene ID	782907
Protein Existence Status	Reviewed
Secondary Information
Protein Function	It catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Also involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.
PTMs	N6-acetylation at Lysine
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Della Ragione F, Oliva A, Gragnaniello V, Russo GL, Palumbo R, Zappia V. Physicochemical and immunological studies on mammalian 5'-deoxy-5'-methylthioadenosine phosphorylase. J Biol Chem. 1990 Apr 15;265(11):6241-6. PMID: 2108157.