Primary Information
BoMiProt ID	Bomi9170
Protein Name	Signal peptidase complex subunit 3/Microsomal signal peptidase 22/23 kDa subunit/SPC22/23/SPase 22/23 kDa subunit
Organism	Bos taurus
Uniprot ID	Q3SZU5
Milk Fraction	Whey
Ref Sequence ID	NP_001070461.1
Aminoacid Length	180
Molecular Weight	20313
FASTA Sequence	Download
Gene Name	SPCS3
Gene ID	767917
Protein Existence Status	reviewed
Secondary Information
Protein Function	is a subunit of the signal peptidase complex (SPC), which cleaves the signal sequences from secretory and membrane proteins during their transport into the lumen of the endoplasmic reticulum.
PTMs	Glycosylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q3SZU5|SPCS3_BOVIN Signal peptidase complex subunit 3 OS=Bos taurus OX=9913 GN=SPCS3 PE=2 SV=1 MNTVLSRANSLFAFSLSVMAALTFGCFITTAFKDRSVPVRLHVSRIMLKNVEDFTGPRER SDLGFITFDITADLENIFDWNVKQLFLYLSAEYSTKNNALNQVVLWDKIVLRGDNPKLLL KDMKTKYFFFDDGNGLKGNRN*141VTLTLSWNVVPNAGILPLVTGSGHVSVPFPDTYEITKSY
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	1TMH; (13-31)
Bibliography	Gao, Y., Jian, L., Lu, W., Xue, Y., Machaty, Z., & Luo, H. (2021). Vitamin E can promote spermatogenesis by regulating the expression of proteins associated with the plasma membranes and protamine biosynthesis. Gene, 773, 145364. https://doi.org/10.1016/j.gene.2020.145364