Primary Information |
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| BoMiProt ID | Bomi9079 |
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| Protein Name | Serpin H1/Collagen-binding protein/Colligin |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KJH6 |
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| Milk Fraction | whey |
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| Ref Sequence ID | NP_001039528.1 |
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| Aminoacid Length | 418 |
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| Molecular Weight | 46507 |
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| FASTA Sequence |
Download |
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| Gene Name | SERPINH1 |
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| Gene ID | 510850 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | molecular maturation of collagen.it recognizes collagenous (Gly-Xaa-Arg) repeats on triple-helical procollagen and can prevent local unfolding and/or aggregate formation of procollagen. |
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| PTMs | Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q2KJH6|SERPH_BOVIN Serpin H1 OS=Bos taurus OX=9913 GN=SERPINH1 PE=2 SV=1
MRALLLISTICLLARALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
DQAVENILLSPVVVASSLGLVSLGGKAATASQAKAVLSAEQLRDDEVHAGLGELLRSLSN*120
STARN*125VTWKLGSRLYGPSSVS*141FAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
TDGKLPEVTKDVERTDGALLVNAMFFKPHWDERFHHKMVDNRGFMVTRSYTVGVTMMHRT
GLYNYYDDEKEKLQMVEMPLAHKLSSLIIIMPHHVEPLERLEKLLTKEQLKVWMGKMQKK
AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWD
TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | no TM helices |
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| Bibliography | Ito S, Nagata K. Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone. Semin Cell Dev Biol. 2017 Feb;62:142-151. doi: 10.1016/j.semcdb.2016.11.005. Epub 2016 Nov 9. PMID: 27838364. |
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