Primary Information |
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BoMiProt ID | Bomi8893 |
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Protein Name | RNA-binding protein 42/RNA-binding motif protein 42 |
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Organism | Bos taurus |
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Uniprot ID | Q0P5L0 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_001069673.1 |
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Aminoacid Length | 448 |
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Molecular Weight | 47187 |
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FASTA Sequence |
Download |
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Gene Name | RBM42 |
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Gene ID | 540172 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | role in the maintenance of cellular ATP level in the stress conditions possibly through protecting their target mRNAs.RBM42 also directly bound to the 3' untranslated region of p21 mRNA, one of the target mRNAs for hnRNP K.hnRNP K is also a RNA-binding protein |
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Biochemical Properties | contains one RRM in its C-terminal region, as a binding partner of hnRNP K.RBM42 directly bound to 3′ UTR of p21 mRNA. |
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PTMs | Acetylation on Ala, Methylation, Phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q0P5L0|RBM42_BOVIN RNA-binding protein 42 OS=Bos taurus OX=9913 GN=RBM42 PE=2 SV=1
MAGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVTGIPTAV
PAVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPV
GFGPGDRSHLDS*132PEAREAMFLRRAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMAR
APGPPLGSMAALRPPLEEPATPRELGLGLGLGLKEKEEAVVAAAAGLEEASAVVAVGAGG
APAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPP
PGLMALEVPEPLSEDKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEV
NDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPI
KLRKSMWKDRNLDVVRKKQKEKKKLGLR
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Predicted Disorder Regions | 5 disordered segments; (2-34), (63-95), (112-123), (320-326), (429-448) |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | Fukuda T, Naiki T, Saito M, Irie K. hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions. Genes Cells. 2009 Feb;14(2):113-28. doi: 10.1111/j.1365-2443.2008.01256.x. Epub 2008 Jan 6. PMID: 19170760. |