Primary Information |
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| BoMiProt ID | Bomi8637 |
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| Protein Name | RAS protein activator like-3 |
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| Organism | Bos taurus |
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| Uniprot ID | A6QQ91 |
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| Milk Fraction | Whey,MFGM |
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| Ref Sequence ID | NP_001095706.1 |
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| Aminoacid Length | 1012 |
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| Molecular Weight | 110755 |
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| FASTA Sequence |
Download |
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| Gene Name | RASAL3 |
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| Gene ID | 540027 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Ras GTPase activating protein (GAP).expressed in hematopoietic cells and stimulates p21ras GTPase activity.Regulation of number and function of NKT cells.Supports survival of naïve T cells. |
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| PTMs | Phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|A6QQ91|RASL3_BOVIN RAS protein activator like-3 OS=Bos taurus OX=9913 GN=RASAL3 PE=2 SV=1
MDPPSPSRASQTQPVAPS*18PLTSYRWHSGGGAEKGAGGFRWGRLAGWGRAQS*51HQETTASSQ
PAPRSLFRRVLSAPPKESRTSRLKISKSLWGKNKSPPLDSEPEPENPEPEPELEPLATQI
PEAPTPDVPVWNIEAFTLLDGKLVLLGNEDEGPRQPRMGS*160AS*162S*163ESS*166IHVASGNLKDPDRTPGKTDPEAAGPHQIHNVRGLLKRLKEKKKAKS*212ELGASASRDGPPS*225ALGS*229RES*232LAT*235ISELDLGAERDVRVWPLHPSLLEEPHCFQVTWAGGSRCFSCRSAAERDRWIEDLRRHFQPSQDNV
EREETWLSVWVHEVKGLPRAAAAAPGVRTELWLDGALLARTTPRAGPGQLFWAERFHFEA
LPPARRLSLRLRGAGPGDAVLGRVALALEELGIPRAPAAGLERWFPLLGAPAGAALRARI
RARRLRVLPSERYKELAEFLTFHYARLCGALELALSAQAKEELAAAMVRVLRATGRAQAL
VTDLGTAELARSGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDC
EVDPSKCPASDLPQHQSRLRNSCKEVFENIIHSYNWFPAELGTVFSGWREACKARGSEAL
GPRLVCASLFLRLLCPAILSPSLFGLALEHPAPGPARTLTLIAKVIQNLANRAPFGEKEA
YMSFMNTFLEDHGPAMQHFLDQVATVDADTAPSGYQGSSDLALQLAVLHAQLCTIFAELD
QATRDNLEPLPTILHAIEEGRPVPVTVPMCLPAPRTQGHSSISAGEKPGFLAPRDLPKHT
PLISKSQS*788LRS*791VHGAGSWARPRLEEEQPPRLPRPVKRTQSVPAGRPARRRPSAGPRPRPK
GSLHAGPAPRGRPWTGASASLPRKPSVPWQRQMDQPRDKDQALGTHRPVGKLAELQCEVA
ALRQDLKMLSGLVESLSTHIRSLSEQQEQLRTQLQLLDSRLREGTAKLDPGRDRSTNEGH
RLKSLECRLAEIESTQAQLKDTIQNLQLLPRTSESQSQPVPLKAPCINGDTT
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| Predicted Disorder Regions | 1-17, 58-126, 162-165, 201-216, 782-786, 936-957, 980-1012 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Muro R, Nitta T, Kitajima M, Okada T, Suzuki H. Rasal3-mediated T cell survival is essential for inflammatory responses. Biochem Biophys Res Commun. 2018 Jan 29;496(1):25-30. doi: 10.1016/j.bbrc.2017.12.159. Epub 2017 Dec 29. PMID: 29291408. |
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