Primary Information |
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| BoMiProt ID | Bomi8519 |
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| Protein Name | Pulmonary surfactant-associated protein A |
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| Organism | Bos taurus |
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| Uniprot ID | Q6RXL1 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001071306.2 |
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| Aminoacid Length | 248 |
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| Molecular Weight | 26381 |
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| FASTA Sequence |
Download |
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| Gene Name | SFTPA1 |
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| Gene ID | 407213 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Surfactant protein-A (SP-A) is a collectin protein expressed in airway epithelia that is critical in the modulation of both innate and adaptive immunity against inhaled pathogens. |
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| PTMs | Disulfide bond, Glycosylation, Hydroxylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q6RXL1|SFTPA_BOVIN Pulmonary surfactant-associated protein A OS=Bos taurus OX=9913 GN=SFTPA1 PE=2 SV=2
MLLCSLTLTLLWMVASGLECDVKEVCLGSPGIPGTPGSHGLPGRDGRDGIKGDPGPPGPM
GPPGGMPGLPGRDGMTGAPGLPGERGEKGEPGERGPPGFPAYLDEELQGTLHEIRHQVLQ
SQGVLRLQGSVLAVGEKVFSTNGQSVNFDAIKELCARVGGHIAAPRSPEENEAIVSIVKK
YNTYAYLGLVEGPTAGDFYYLDGAPVN*207YTNWYPGEPRGRGKEKCVEIYTDGQWNDKNCLQ
YRLAICEF
|
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| Predicted Disorder Regions | 1 disordered segment; (20-99) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Chang EH. The role of surfactant protein-A in sinusitis. Curr Opin Allergy Clin Immunol. 2019 Feb;19(1):26-29. doi: 10.1097/ACI.0000000000000500. PMID: 30507715. |
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