Search by BoMiProt ID - Bomi8376

Primary Information

BoMiProt ID Bomi8376
Protein Name Protein odd-skipped-related 1
Organism Bos taurus
Uniprot IDQ08DS3
Milk FractionWhey
Ref Sequence ID NP_001070384.2
Aminoacid Length 267
Molecular Weight 29626
FASTA Sequence Download
Gene Name OSR1/ODD1
Gene ID 539430
Protein Existence Status reviewed

Secondary Information

Protein Function Odd-skipped related 1 (Osr1) is known to play important roles in embryonic, heart, and urogenital development. It is also an essential regulator of heart and urogenital development
Biochemical Properties Mouse Osr1 has a 65% homology with Osr2, whereas their tissue distribution difers. Human Osr1 has been detected in fetal lung, adult colon, small intestine, prostate, and testis tissues is specifcally expressed in limb, tooth, and kidney tissues .
PTMs Methylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments Odd 1(-/-) mutant mouse embryos fail to form atrial septum, display dilated atria with hypoplastic venous valves, and exhibit blood backflow from the heart into systemic veins.
Bibliography 1.Kawai S, Yamauchi M, Amano A. Zinc-finger transcription factor Odd-skipped related 1 regulates cranial bone formation. J Bone Miner Metab. 2018 Nov;36(6):640-647. doi: 10.1007/s00774-017-0885-9. Epub 2017 Dec 12. PMID: 29234951. 2.Wang Q, Lan Y, Cho ES, Maltby KM, Jiang R. Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development. Dev Biol. 2005 Dec 15;288(2):582-94. doi: 10.1016/j.ydbio.2005.09.024. Epub 2005 Oct 11. PMID: 16223478; PMCID: PMC3869089.