Primary Information
BoMiProt ID	Bomi8340
Protein Name	Protein inturned/Inturned planar cell polarity effector homolog/PDZ domain-containing protein 6
Organism	Bos taurus
Uniprot ID	F1MDL2
Milk Fraction	Whey,MFGM
Ref Sequence ID	NP_001192784.1
Aminoacid Length	933
Molecular Weight	104454
FASTA Sequence	Download
Gene Name	INTU/PDZD6
Gene ID	519372
Protein Existence Status	reviewed
Secondary Information
Protein Function	Imp role in ciliogenesis and embryonic development.coordinating the interaction between cilia-associated proteins and actin-nucleation factors.organization of the actin cytoskeleton.
PTMs	Phosphorylation on Ser
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|F1MDL2|INTU_BOVIN Protein inturned OS=Bos taurus OX=9913 GN=INTU PE=3 SV=2 MASLPLCGSVRSPEGLPGDPSSQEDRQDYDPEDPVSGSGSYSPTSTDSNDLEPEWLDSVQ KNGELFYLELSEDEEESLLPETPTVNHVRFSENEIIIEEDDYREGKKYEPKLKRFTKILK SKKLLPKRYNKKNSNASGPVSILKHQSNQKMGVIVQQRHKDVNIYVNPKKLTVTKAKEQL KLLEVLVGIIHQTKWSWRRTGKQGGGERLVVHGLLPGGSAMKSGQVLIGDVLVAVNDVEV TSENIERVLSCIPGPMQVKLTFENAYAMKKETTQPRQKKAQLNTSDLVKLLWGEEVEGIQ QNILNTPHIVMYLTLQLDSETSKEEQEILYHYPVSEASQKLQSVRGIFLTLCDMLENVTG TQVTSSSLLLNRKQIHIAYWKETDKLLLIGLPAEEVPLPQLRNMIEDVAQTLKFMYGSLD SAFCQVENVPRLDHFFSLFFQRALQPTKLHSSASPSTQQYDASSAVLLDNLPGVRWLTLP QEIKLELDTALSDLEAADFAELSEDYYDMRRLYTILGSSLFYKGYLICSHLPKDDLIDIA VYCRHYCLLPLAAKQRIGQLVIWREVFPRHHLQPSADSNTEVFQEPEGRYFLLIVGLRHY MLCVLLEAGGCASRAIGNPGPDCIYVDQVKTTLHQLEGVDSRINERLASSPTPCLSCADW FLAGSHEKLDNLTTS*675PILSRLHGASRVATSPTCRRTLFSDYSLKTRKPSPSRSGGPDSGL EGEGVGLSPHTTESQGSHGSEETGALLKVTKKKSALPNPFHLGNLKKDLSEKELDIYNTV KLTSGPENTLFHYVALETVQGIFITPTHEEVAQLSGSIHPQLIKNFHQCCLSIRAVFQQT VAKEKKKALNGKDHSGSTNSVSSLNPVKEHGVLFECSPENWTDQRKAPPVMAYWVVGRLF LHPKLQELYVCFHDSVTEIAIEMAFKLFFGLTL
Predicted Disorder Regions	1-70, 121-140, 707-746, 845-859
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G. The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol. 2015 Dec 7;211(5):963-73. doi: 10.1083/jcb.201502043. PMID: 26644512; PMCID: PMC4674276.