Search by BoMiProt ID - Bomi8337

Primary Information

BoMiProt ID Bomi8337
Protein Name Protein FAM89A
Organism Bos taurus
Uniprot IDA6QQF7
Milk FractionWhey
Ref Sequence ID NP_001094727.1
Aminoacid Length 178
Molecular Weight 18888
FASTA Sequence Download
Gene Name FAM89A
Gene ID 616421
Protein Existence Status reviewed

Secondary Information

Protein Function immune responses pathways and various pathologies such as atherosclerosis and glioma cell expression.
Biochemical Properties molecular mass of 18.6kDa and a predicted isoelectric point of 5.64. 184 amino acids in length.Composition of FAM89A protein is notable for its abundance of four amino acids; Leucine (14.1%), Glycine (12.0%), Alanine (11.4%) and Serine (11.4%). FAM89A shows five periodic repeats of leucine residues at every seventh amino acid position at positions 81-115, which is characteristic of its predicted leucine zipper structural motif.conserved leucine-rich adapter protein domain (LURAP) called PF14854 located at amino acid positions 84-122.FAM89A is predicted to be 40% alpha helix, 11% extended strand, and 49% random coils.
PTMs Phosphorylation/O-Linked β-N-acetylglucosamine,Glycation,SUMOylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 4 disordered segments; (1-11), (23-41), (55-75), (121-171)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Gómez-Carballa A, Cebey-López M, Pardo-Seco J, Barral-Arca R, Rivero-Calle I, Pischedda S, Currás-Tuala MJ, Gómez-Rial J, Barros F, Martinón-Torres F, Salas A. A qPCR expression assay of IFI44L gene differentiates viral from bacterial infections in febrile children. Sci Rep. 2019 Aug 13;9(1):11780. doi: 10.1038/s41598-019-48162-9. PMID: 31409879; PMCID: PMC6692396.