Primary Information |
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| BoMiProt ID | Bomi8330 |
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| Protein Name | Protein FAM110B |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KJ38 |
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| Milk Fraction | Whey,MFGM |
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| Ref Sequence ID | NP_001070486.1 |
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| Aminoacid Length | 380 |
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| Molecular Weight | 40530 |
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| FASTA Sequence |
Download |
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| Gene Name | FAM110B |
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| Gene ID | 767946 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | is a component of the centrosome associated proteins. |
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| PTMs | phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q2KJ38|F110B_BOVIN Protein FAM110B OS=Bos taurus OX=9913 GN=FAM110B PE=2 SV=1
MPTESLQTGSMVKPVSPAGTFTSAVPLRILNKGPDYFRRQAEPNPKRLSAVERLEADKAK
YVKSQEVINAKQEPVKPAVLAKPPVCPAAKRALGSPTLKGFGGGGGGAKSEGGAPRETLK
LEILKNILNSSEGSSTGSGHKHSARNWPAPRADAAELHRHSFAESLRARPAPGRGSPQEG
GSHVGRRPPEPTSSAAAAADAFLHVSHSSSDIRQGPGARPLKAILPCSSSAPPLPPKPKV
AAPAAVKS*248PEAEAAEPAGGVGRRPSLQRSKSDLSDRYFRVDADVERFFNYCGLDPEELEN
LGMENFARANS*311DIISLNFRSASMISSDCEQSQDSNSDLRNDDSANDRVPYGISAIERNAR
IIKWLYSIKQARESQKVSHV
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| Predicted Disorder Regions | 6 disordered segments; (2-24), (33-63), (72-186), (198-275), (321-347), (376-380) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | overexpression of FAM110B restricts the proliferation and invasion of NSCLC cells by inhibiting Wnt/β-catenin signaling. |
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| Bibliography | Xie M, Cai L, Li J, Zhao J, Guo Y, Hou Z, Zhang X, Tian H, Li A, Miao Y. FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling. Onco Targets Ther. 2020 May 19;13:4373-4384. doi: 10.2147/OTT.S247491. PMID: 32547070; PMCID: PMC7245470. |
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