Primary Information
BoMiProt ID	Bomi8328
Protein Name	Protein FAM107B
Organism	Bos taurus
Uniprot ID	Q2KI00
Milk Fraction	whey
Ref Sequence ID	NP_001039858.1
Aminoacid Length	131
Molecular Weight	15586
FASTA Sequence	Download
Gene Name	FAM107B
Gene ID	535023
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Probably act as as a heat shock protein.
Biochemical Properties	The Family with sequence similarity 107 (FAM107) possesses an N-terminal domain of unknown function (DUF1151) that is highly conserved beyond species and C-terminal (aa 61-112) variable coiled-coil region.Has a nuclear localization signal (NLS) in the center of the protein sequences.
PTMs	Acetylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	(1-131)
DisProt Annotation
TM Helix Prediction	No TM helices
Additional Comments	FAM107B expression was decreased in stomach cancer and other cancers also.
Bibliography	1.Nakajima H, Ishigaki Y, Xia QS, Ikeda T, Yoshitake Y, Yonekura H, Nojima T, Tanaka T, Umehara H, Tomosugi N, Takata T, Shimasaki T, Nakaya N, Sato I, Kawakami K, Koizumi K, Minamoto T, Motoo Y. Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation. Int J Oncol. 2010 Sep;37(3):583-93. doi: 10.3892/ijo_00000707. PMID: 20664927. 2.Guo, J., Bian, Y., Wang, Y., Chen, L., Yu, A., & Sun, X. (2017). FAM107B is regulated by S100A4 and mediates the effect of S100A4 on the proliferation and migration of MGC803 gastric cancer cells. Cell biology international, 41(10), 1103–1109. https://doi.org/10.1002/cbin.10816