Search by BoMiProt ID - Bomi8302


Primary Information

BoMiProt ID Bomi8302
Protein Name Proteasome subunit alpha type-3
Organism Bos taurus
Uniprot IDQ58DU5
Milk FractionExosomes
Ref Sequence ID NP_001029407.1
Aminoacid Length 255
Molecular Weight 28405
FASTA Sequence Download
Gene Name PSMA3
Gene ID 505176
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.
Protein Function It is a component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.
PTMs N6-acetylation at Lysine,Phosphorylation at Serine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q58DU5|PSA3_BOVIN Proteasome subunit alpha type-3 OS=Bos taurus OX=9913 GN=PSMA3 PE=1 SV=3 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGEITNGRHEIVPKDVREEAEKYA KES*243LKEEDES*250DDDNM
SCOP Class : Alpha and beta proteins (a+b)
Fold : Type II GAT domain-like
Superfamily : Class II glutamine amidotransferases
Family : Proteasome subunits
Domain Name : 1IRU G:1-245

CATH Matched CATH superfamily
3.60.20.10
Predicted Disorder Regions 1-4, 238-255
DisProt Annotation
TM Helix Prediction No TM helices
PDB ID 1IRU, 7DR6, 7DR7, 7DRW,