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Primary Information | |
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| BoMiProt ID | Bomi8302 |
| Protein Name | Proteasome subunit alpha type-3 |
| Organism | Bos taurus |
| Uniprot ID | Q58DU5 |
| Milk Fraction | Exosomes |
| Ref Sequence ID | NP_001029407.1 |
| Aminoacid Length | 255 |
| Molecular Weight | 28405 |
| FASTA Sequence | Download |
| Gene Name | PSMA3 |
| Gene ID | 505176 |
| Protein Existence Status | Reviewed |
Secondary Information | |
| Presence in other biological fluids/tissue/cells | Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. |
| Protein Function | It is a component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. |
| PTMs | N6-acetylation at Lysine,Phosphorylation at Serine |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | >sp|Q58DU5|PSA3_BOVIN Proteasome subunit alpha type-3 OS=Bos taurus OX=9913 GN=PSMA3 PE=1 SV=3 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGEITNGRHEIVPKDVREEAEKYA KES*243LKEEDES*250DDDNM |
| SCOP | Class : Alpha and beta proteins (a+b) Fold : Type II GAT domain-like Superfamily : Class II glutamine amidotransferases Family : Proteasome subunits Domain Name : 1IRU G:1-245 |
| CATH | Matched CATH superfamily 3.60.20.10 |
| Predicted Disorder Regions | 1-4, 238-255 |
| DisProt Annotation | |
| TM Helix Prediction | No TM helices |
| PDB ID | 1IRU, 7DR6, 7DR7, 7DRW, |