Primary Information |
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| BoMiProt ID | Bomi8199 |
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| Protein Name | Pre-B-cell leukemia transcription factor-interacting protein 1 |
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| Organism | Bos taurus |
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| Uniprot ID | A6QLY7 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001068733.1 |
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| Aminoacid Length | 727 |
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| Molecular Weight | 80258 |
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| FASTA Sequence |
Download |
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| Gene Name | PBXIP1 |
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| Gene ID | 506485 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling |
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| PTMs | Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|A6QLY7|PBIP1_BOVIN Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Bos taurus OX=9913 GN=PBXIP1 PE=2 SV=1
MASCPDSDNSWVLAGSESLPVETLGPESGNDPESERAPRAPQS*43PSRAAAEESAGTLDGGE
TVSQNESSKSGPILSEEAEAKQGVLEGDDPGVESPGPGDTEAQGDLEETPEVVGLEPDSQ
DLEDQSPHRS*130LPSS*134PKTAWIREEAHHS*147S*148S*149DDDT*153DVDVEGLRRRRGREPGTPQPAATLGVEDQVQGEGAGGQLGISLNMCLLGSLVLLGLGVLLFGGLSESESGPLEEVDLQVLPDVESDT
EMLEAVGDGQDGLQQLQTSEVLDSVPSLQNMALLLDKLAKENQDIRLLQAQLQAQKEELQ
SLMRQPKGLEEENARLRGALQQGEASQRALESELQQLRAQLQGLEADCVQGADGLCLQWG
RGPQAGQVTKEQGPTGQEPSPGFLEQKKQLEAEAQALRQELERQRRLLGSVQQDLERSLK
EAGRGDPARAGLAELGHRLAQKLRGLENWGQHPGVPANVSEAWHQKPHFQNSREPSGKEK
WWDRQGDWKTEHWKHKKEASGREKSWRGEEDRELVGRRKEGKPRVEEWAGKKDGKQQRSK
EPPRKSGRPHPSGERQKHPRWKEGAKDRHDPLPLWAELSRHKYQAPQGCSGVHECARQEG
LAFFGIELAPVRQQELASLLRTYLARLPWAGPLTEELPLSPAYFGEDGIFRHDRLRFRDF
VDALEDQLEEVAVRQTGDDDAVDDFEDFIFSHFFGDKALKKRSGKKDKHLQNRVVGPREE
HSPHRQG
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| Predicted Disorder Regions | 1-135, 491-568, 701-727 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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