Primary Information |
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| BoMiProt ID | Bomi8132 |
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| Protein Name | Polycomb complex protein BMI-1/Polycomb group RING finger protein 4 |
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| Organism | Bos taurus |
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| Uniprot ID | Q32KX7 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001033161.1 |
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| Aminoacid Length | 326 |
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| Molecular Weight | 36966 |
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| FASTA Sequence |
Download |
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| Gene Name | BMI1/PCGF4 |
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| Gene ID | 510666 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, role in the regulation of Hox gene expression, X-chromosome inactivation, tumorigenesis, and stem cell self-renewal.monoubiquitination of histone H2A 'Lys-119' |
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| PTMs | ubl conjugation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 102-122, 228-326 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Li Z, Cao R, Wang M, Myers MP, Zhang Y, Xu RM. Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex. J Biol Chem. 2006 Jul 21;281(29):20643-9. doi: 10.1074/jbc.M602461200. Epub 2006 May 18. PMID: 16714294. |
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