Primary Information |
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BoMiProt ID | Bomi8099 |
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Protein Name | Pleiotropic regulator 1 |
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Organism | Bos taurus |
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Uniprot ID | Q2KID6 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_001039827.1 |
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Aminoacid Length | 513 |
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Molecular Weight | 56789 |
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FASTA Sequence |
Download |
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Gene Name | PLRG1 |
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Gene ID | 533951 |
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Protein Existence Status | reviewed |
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Secondary Information |
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PTMs | N-Acetylation at Meth, Phosphorylation at Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q2KID6|PLRG1_BOVIN Pleiotropic regulator 1 OS=Bos taurus OX=9913 GN=PLRG1 PE=2 SV=1
MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
SKENLKEKVPQNASDSYGHKQYPANQGQEVEYLVTGTHPYPPGPGVALTADTKIQRMPS*119E
SAAQSLAVALPASQARADANRPVPAGGEYRHPGAPDRAQPAGAVVMEGSNAKNSALMAKK
APTMPKPQWHPPWKLYRVIS*200GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLS
LTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTID
VLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVA
GKTRVTLTNHKKSVRAVVLHPRHYTFASGS*390PDNIKQWKFPDGSFIQNLSGHNAIINTLTV
NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAE
ADKTIKVYKEDDTATEETHPVSWKPEIIKRKRF
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Predicted Disorder Regions | 29-36, 59-160 |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Additional Comments | The NF-κB (nuclear factor κB) transcription factor family is a pleiotropic regulator of many cellular pathways, providing a mechanism for the cell to respond to a wide variety of stimuli and environmental challenges. |
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Bibliography | 1.Ledoux AC, Perkins ND. NF-κB and the cell cycle. Biochem Soc Trans. 2014 Feb;42(1):76-81. doi: 10.1042/BST20130156. PMID: 24450631. |