Primary Information |
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| BoMiProt ID | Bomi8045 |
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| Protein Name | Placental prolactin-related protein 2/PRC-II/bPRCII |
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| Organism | Bos taurus |
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| Uniprot ID | P12401 |
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| Milk Fraction | Whey |
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| Aminoacid Length | 267 |
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| Molecular Weight | 30322 |
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| FASTA Sequence |
Download |
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| Gene Name | PRP2 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | found in the placenta of ruminants.placental and fetal development in cattle. function in pregnancy coordination,
immunoregulation and regulation of implantation at
the fetomaternal interface. |
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| Biochemical Properties | 267 aa long. |
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| Significance in milk | bovine placental lactogen |
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| PTMs | glycosylation,phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|P12401|PLRP2_BOVIN Placental prolactin-related protein 2 OS=Bos taurus OX=9913 GN=PRP2 PE=2 SV=1
MVETRLGWEAGGGLGAPGGPGGKLGGLGLAVGGTHSWSGLLKRVDRREARAQPRLLVLGC
LLCQGISCPSCGPDMFVSLQKSLIDVFINAASLSHDFHN*99LSTIMFNEFDEKYAQGKLYYI
N*121ATKSCHTNSFHTPEERDKAQQMNNEDLSKWTLVLLYSWNNPLYYLLLELRNMKNLSEAV
ISSAMEIENMSEKLQAFIESQFRKIIVPVLKMIHEVSNTWSRFSSMTFSDEDRSISEYYN
LFYCLRRDSRKVDMYIKILTCRTRKTC
|
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Significance of PTMs | four N-glycosylation sites were located at aa positions 35–37 and 57–50 in bPRP-II.phosphorylation of Ser at position 90. |
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| Bibliography | USHIZAWA, K., & HASHIZUME, K. (2006). Biology of the prolactin family in bovine placenta. II. Bovine prolactin‐related proteins: Their expression, structure and proposed roles. Animal Science Journal, 77(1), 18-27. |
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