Primary Information |
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BoMiProt ID | Bomi7964 |
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Protein Name | Phosphatidylserine lipase ABHD16A/Alpha/beta hydrolase domain-containing protein 16A/Abhydrolase domain-containing protein 16A/HLA-B-associated transcript 5 homolog/Monoacylglycerol lipase ABHD16A |
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Organism | Bos taurus |
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Uniprot ID | Q1JPD2 |
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Milk Fraction | Whey,MFGM |
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Ref Sequence ID | NP_001069073.1 |
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Aminoacid Length | 558 |
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Molecular Weight | 63304 |
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FASTA Sequence |
Download |
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Gene Name | ABHD16A |
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Gene ID | 513252 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | These proteins could play an important role in the regulation of lipid metabolism and signalling transduction pathways, and are possibly directly or indirectly correlated with several human diseases. |
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Biochemical Properties | ABHD16A has acylglycerol lipase and phosphatidylserine lipase activities. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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Predicted Disorder Regions | NA |
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DisProt Annotation | |
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TM Helix Prediction | 2TMHs; (60-82), (95-117) |
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Additional Comments | Other members of the ABHD protein family are associated with different diseases, such as cancer, lipid metabolism, liver disease and pulmonary disease. |
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Bibliography | Xu J, Gu W, Ji K, Xu Z, Zhu H, Zheng W. Sequence analysis and structure prediction of ABHD16A and the roles of the ABHD family members in human disease. Open Biol. 2018 May;8(5):180017. doi: 10.1098/rsob.180017. PMID: 29794032; PMCID: PMC5990648. |