Primary Information
BoMiProt ID	Bomi7852
Protein Name	PCNA-associated factor
Organism	Bos taurus
Uniprot ID	Q5E9B2
Milk Fraction	Whey,exosome
Ref Sequence ID	NP_001015678.1
Aminoacid Length	111
Molecular Weight	11910
FASTA Sequence	Download
Gene Name	PCLAF
Gene ID	540737
Protein Existence Status	reviewed
Secondary Information
Protein Function	regulator of DNA repair during DNA replication. P15PAF (KIAA0101) was significantly upregulated in high-grade serous ovarian cancer (HGSOC).
PTMs	Acetylation, Phosphorylation, Ubl conjugation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q5E9B2|PAF15_BOVIN PCNA-associated factor OS=Bos taurus OX=9913 GN=PCLAF PE=3 SV=1 MVRTKANS*8VPGSYRKVVASRAPRKVLGS*28STS*31AANSTPLSSRKAENKYAGGNPVCVRPTPK WQKGIGEFFSLS*72PKDSEKENRIPEEAGSSGLGKAKRKACPLPPDHTDDEKE
Predicted Disorder Regions	1 disordered segment; (1-111)
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Jin C, Liu Z, Li Y, Bu H, Wang Y, Xu Y, Qiu C, Yan S, Yuan C, Li R, Diao N, Zhang Z, Wang X, Liu L, Kong B. PCNA-associated factor P15PAF , targeted by FOXM1, predicts poor prognosis in high-grade serous ovarian cancer patients. Int J Cancer. 2018 Dec 1;143(11):2973-2984. doi: 10.1002/ijc.31800. Epub 2018 Oct 4. PMID: 30129654.