Primary Information |
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| BoMiProt ID | Bomi7828 |
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| Protein Name | Paraspeckle component 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q1LZD9 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001068745.1 |
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| Aminoacid Length | 520 |
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| Molecular Weight | 58275 |
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| FASTA Sequence |
Download |
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| Gene Name | PSPC1 |
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| Gene ID | 506696 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | cellular stress responses, cell differentiation, corpus luteum formation and cancer progression.androgen receptor co-activator.detected in differentiating Sertoli cell nuclei from day 15 onwards, as they develop androgen responsiveness. |
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| PTMs | Acetylation on Met, Methylation on Arg, Phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q1LZD9|PSPC1_BOVIN Paraspeckle component 1 OS=Bos taurus OX=9913 GN=PSPC1 PE=2 SV=1
MMLRGNLKQVRIEKNPARLRALESAAGEGDPAALALALPGEPPVPAAPAGEDRPADEGGF
TIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEDDFKRLFERYGEPSEVFINRDRGFGFIR
LESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVE
KAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDG
LPEKLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEK
LEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEM
IRHREQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFS*406PAPAGNQGPPAMMG
MNMNNRGTIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPS*470QMGS*474PMGSRT
GSETPQAPMSGVGPVSGGPGGFGRGS*506QGANFEGPNKRRRY
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| Predicted Disorder Regions | 2 disordered segments; (32-56), (368-373) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Hupalowska A, Jedrusik A, Zhu M, Bedford MT, Glover DM, Zernicka-Goetz M. CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development. Cell. 2018 Dec 13;175(7):1902-1916.e13. doi: 10.1016/j.cell.2018.11.027. PMID: 30550788; PMCID: PMC6292842. |
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