Search by BoMiProt ID - Bomi7828


Primary Information

BoMiProt ID Bomi7828
Protein Name Paraspeckle component 1
Organism Bos taurus
Uniprot IDQ1LZD9
Milk FractionWhey
Ref Sequence ID NP_001068745.1
Aminoacid Length 520
Molecular Weight 58275
FASTA Sequence Download
Gene Name PSPC1
Gene ID 506696
Protein Existence Status reviewed

Secondary Information

Protein Function cellular stress responses, cell differentiation, corpus luteum formation and cancer progression.androgen receptor co-activator.detected in differentiating Sertoli cell nuclei from day 15 onwards, as they develop androgen responsiveness.
PTMs Acetylation on Met, Methylation on Arg, Phosphorylation on Ser
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q1LZD9|PSPC1_BOVIN Paraspeckle component 1 OS=Bos taurus OX=9913 GN=PSPC1 PE=2 SV=1 MMLRGNLKQVRIEKNPARLRALESAAGEGDPAALALALPGEPPVPAAPAGEDRPADEGGF TIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEDDFKRLFERYGEPSEVFINRDRGFGFIR LESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVE KAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLLTTTPRPVIVEPMEQFDDEDG LPEKLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALDEMEKQQREQVDRNIREAKEK LEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEM IRHREQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFS*406PAPAGNQGPPAMMG MNMNNRGTIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPS*470QMGS*474PMGSRT GSETPQAPMSGVGPVSGGPGGFGRGS*506QGANFEGPNKRRRY
Predicted Disorder Regions 2 disordered segments; (32-56), (368-373)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Hupalowska A, Jedrusik A, Zhu M, Bedford MT, Glover DM, Zernicka-Goetz M. CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development. Cell. 2018 Dec 13;175(7):1902-1916.e13. doi: 10.1016/j.cell.2018.11.027. PMID: 30550788; PMCID: PMC6292842.