Primary Information
BoMiProt ID	Bomi7741
Protein Name	Omega-amidase NIT2/Nitrilase homolog 2
Organism	Bos taurus
Uniprot ID	Q2T9R6
Milk Fraction	Exosomes
Ref Sequence ID	NP_001033222.1
Aminoacid Length	276
Molecular Weight	30518
FASTA Sequence	Download
Gene Name	NIT2
Gene ID	520620
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Nit2/ω-amidase catalyzes the hydrolysis of α-ketoglutaramate (KGM, the α-keto acid analogue of glutamine) to α-ketoglutarate and ammonia. The enzyme also catalyzes the amide hydrolysis of monoamides of 4- and 5-C-dicarboxylates, including α-ketosuccinamate (KSM, the α-keto acid analogue of asparagine) and succinamate (SM).
PTMs	N6-acetylation at Lysine
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Epova EY, Shevelev AB, Shurubor YI, Cooper AJL, Biryukova YK, Bogdanova ES, Tyno YY, Lebedeva AA, Krasnikov BF. A novel efficient producer of human ω-amidase (Nit2) in Escherichia coli. Anal Biochem. 2021 Nov 1;632:114332. doi: 10.1016/j.ab.2021.114332. Epub 2021 Aug 12. PMID: 34391728. 2.