Search by BoMiProt ID - Bomi7740

Primary Information

BoMiProt ID Bomi7740
Protein Name Oligosaccharyltransferase complex subunit OSTC
Organism Bos taurus
Uniprot IDQ2KID7
Milk FractionWhey
Ref Sequence ID NP_001070560.1
Aminoacid Length 149
Molecular Weight 16769
FASTA Sequence Download
Gene Name OSTC
Gene ID 768033
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells  abomasum 
Protein Function Mammalian oligosaccharyltransferase complex subunit OSTC/DC2 protein has recently been shown to be a new subunit of the oligosaccharyltransferase.
Biochemical Properties OSTC/DC2 is weakly homologous to the C-terminal halves of the yeast oligosaccharyltransferase components Ost3p and Ost6p, which suggests that OSTC/DC2 is a mammalian counterpart of the oligosaccharyltransferase complex subunit involved with glycosylation during protein synthesis.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction 3TMHs; (32-54),(82-104),(117-139)
Bibliography 1.T. Shibatani, L.L. David, A.L. McCormack, K. Frueh, W.R. Skach. Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. Biochemistry. 2005; 44: 5982–5992. 2.Chen CM, Tseng CN, Cho JJ, Lee YZ, Kao CL, Cheng YB, Hong YR, Cho CL. Heat shock induces expression of OSTC/DC2, a novel subunit of oligosaccharyltransferase, in vitro and in vivo. Kaohsiung J Med Sci. 2014 May;30(5):219-23. doi: 10.1016/j.kjms.2014.01.003. Epub 2014 Mar 2. PMID: 24751383.