Primary Information
BoMiProt ID	Bomi7740
Protein Name	Oligosaccharyltransferase complex subunit OSTC
Organism	Bos taurus
Uniprot ID	Q2KID7
Milk Fraction	Whey
Ref Sequence ID	NP_001070560.1
Aminoacid Length	149
Molecular Weight	16769
FASTA Sequence	Download
Gene Name	OSTC
Gene ID	768033
Protein Existence Status	Reviewed
Secondary Information
Presence in other biological fluids/tissue/cells	abomasum
Protein Function	Mammalian oligosaccharyltransferase complex subunit OSTC/DC2 protein has recently been shown to be a new subunit of the oligosaccharyltransferase.
Biochemical Properties	OSTC/DC2 is weakly homologous to the C-terminal halves of the yeast oligosaccharyltransferase components Ost3p and Ost6p, which suggests that OSTC/DC2 is a mammalian counterpart of the oligosaccharyltransferase complex subunit involved with glycosylation during protein synthesis.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	3TMHs; (32-54),(82-104),(117-139)
Bibliography	1.T. Shibatani, L.L. David, A.L. McCormack, K. Frueh, W.R. Skach. Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. Biochemistry. 2005; 44: 5982–5992. 2.Chen CM, Tseng CN, Cho JJ, Lee YZ, Kao CL, Cheng YB, Hong YR, Cho CL. Heat shock induces expression of OSTC/DC2, a novel subunit of oligosaccharyltransferase, in vitro and in vivo. Kaohsiung J Med Sci. 2014 May;30(5):219-23. doi: 10.1016/j.kjms.2014.01.003. Epub 2014 Mar 2. PMID: 24751383.