Primary Information |
|---|
| BoMiProt ID | Bomi7684 |
|---|
| Protein Name | Nucleolar protein 56/Nucleolar protein 5A |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | Q3SZ63 |
|---|
| Milk Fraction | Whey |
|---|
| Ref Sequence ID | NP_001028794.1 |
|---|
| Aminoacid Length | 596 |
|---|
| Molecular Weight | 66331 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | NOP56/NOL5A |
|---|
| Gene ID | 404165 |
|---|
| Protein Existence Status | reviewed |
|---|
Secondary Information |
|---|
| Protein Function | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity). |
|---|
| Biochemical Properties | Part of a large pre-ribosomal ribonucleoprotein (RNP) complex, that consists of at least 62 ribosomal proteins, 45 nonribosomal proteins and both pre-rRNA and mature rRNA species. Within this complex directly interacts with TCOF1 in an RNA-independent manner. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles; the core proteins SNU13, NOP56, NOP58 and FBL assemble stepwise onto the snoRNA. |
|---|
| PTMs | Acetylation, Isopeptide bond formation, Methylation at Arg, Phosphorylation at Ser, Ubl conjugation |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q3SZ63|NOP56_BOVIN Nucleolar protein 56 OS=Bos taurus OX=9913 GN=NOP56 PE=2 SV=1
MVLLHVLFEHAVGYALLALKEVEEIILLLPQVEECVLNLGKFHNIVRLVAFCPFSSSQVA
LENANAVSEGVVHEDLRLLLETHLPPKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAE
ILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDK
DINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRKELNEEKLEKLEELTMDAAK
AKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALI
GEAVGARLIAHAGS*314LTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRA
AAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDV
MKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAAIALASSENS*465S*466APEECEETSERPKK
KKKQKPQEVLQENGMEDPSVSFSKPKKKKS*510FSKEELVS*518S*519DLEETAGTGSLPKRKKS*536FPKEEPVTDPDESENKRVPKKKRKLS*562PKEEPLS*569S*570GPEEAAASKSS*581GS*583KKKKKLRKLSQES
|
|---|
| Predicted Disorder Regions | 87-92, 429-596 |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
