Primary Information
BoMiProt ID	Bomi7604
Protein Name	Notchless protein homolog 1
Organism	Bos taurus
Uniprot ID	Q58D20
Milk Fraction	Whey
Ref Sequence ID	NP_001014887.1
Aminoacid Length	486
Molecular Weight	53229
FASTA Sequence	Download
Gene Name	NLE1
Gene ID	509793
Protein Existence Status	reviewed
Secondary Information
Protein Function	proper embryonic development.survival of cells of the inner cell mass upon implantation.axial skeleton formation
PTMs	phosphorylation on Ser
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q58D20|NLE1_BOVIN Notchless protein homolog 1 OS=Bos taurus OX=9913 GN=NLE1 PE=2 SV=3 MAAAAAADEAATRDVQRLLVQFQDEGGQLLGSPFDVPVDITPDKLQLVCNALLAQEDPLP LAFYVHDAEIVSSLGRTLES*80QAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVIS VAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQ ILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCE RTLTGHAQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDY ALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPA EDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ IAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKC LRIWRR
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Beck-Cormier S, Escande M, Souilhol C, Vandormael-Pournin S, Sourice S, Pilet P, Babinet C, Cohen-Tannoudji M. Notchless is required for axial skeleton formation in mice. PLoS One. 2014 May 29;9(5):e98507. doi: 10.1371/journal.pone.0098507. PMID: 24875805; PMCID: PMC4038589.