Primary Information |
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| BoMiProt ID | Bomi7464 |
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| Protein Name | Neuropeptide Y receptor type 2/NPY-Y2 receptor/NPY2-R/Y2 receptor |
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| Organism | Bos taurus |
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| Uniprot ID | P79113 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_776826.1 |
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| Aminoacid Length | 384 |
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| Molecular Weight | 42943 |
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| FASTA Sequence |
Download |
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| Gene Name | NPY2R |
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| Gene ID | 281943 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Receptor for neuropeptide Y and peptide YY,hypothalamic regulator of feeding behavior,metabolism, and energy homeostasis in both rodents and humans.neuropeptide Y is known to regulate bone homeostasis. |
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| PTMs | Disulfide bond formation, Glycosylation, Lipidation, Palmitoylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 1-44, 262-267, 371-384 |
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| DisProt Annotation | |
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| TM Helix Prediction | 7TMHs; (55-77),(90-112),(131-149),(167-189),(220-242),(272-294) & (309-331) |
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| Additional Comments | knock-out mice for the gene neuropeptide Y 2 receptor, NPY2R, exhibit hyperphagia and excessive weight gain |
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| Bibliography | Maron JL, Johnson KL, Dietz JA, Chen ML, Bianchi DW. Neuropeptide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate. PLoS One. 2012;7(5):e37870. doi: 10.1371/journal.pone.0037870. Epub 2012 May 21. PMID: 22629465; PMCID: PMC3357390. |
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