Primary Information | |
---|---|
BoMiProt ID | Bomi7366 |
Protein Name | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondria/Complex I-SGDH/NADH-ubiquinone oxidoreductase SGDH subunit/CI-SGDH |
Organism | Bos taurus |
Uniprot ID | Q02380 |
Milk Fraction | Whey,MFGM |
Ref Sequence ID | NP_788829.1 |
Aminoacid Length | 189 |
Molecular Weight | 21589 |
FASTA Sequence | Download |
Gene Name | NDUFB5 |
Gene ID | 338061 |
Protein Existence Status | Reviewed |
Secondary Information | |
Protein Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Significance in milk | probablybregulate milk fat synthesis in bovine primary mammary epithelial cells (BMECs) |
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | NA |
CATH | Matched CATH superfamily n/a |
Predicted Disorder Regions | 1-15, 179-189 |
DisProt Annotation | |
TM Helix Prediction | 1TMH; (70-92) |
PDB ID | 5LC5,5LDW,5LDX,5O31, |
Bibliography | Walker, J. E., Arizmendi, J. M., Dupuis, A., Fearnley, I. M., Finel, M., Medd, S. M., Pilkington, S. J., Runswick, M. J., & Skehel, J. M. (1992). Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction. Journal of molecular biology, 226(4), 1051–1072. https://doi.org/10.1016/0022-2836(92)91052-q |