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Primary Information | |
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| BoMiProt ID | Bomi7366 |
| Protein Name | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondria/Complex I-SGDH/NADH-ubiquinone oxidoreductase SGDH subunit/CI-SGDH |
| Organism | Bos taurus |
| Uniprot ID | Q02380 |
| Milk Fraction | Whey,MFGM |
| Ref Sequence ID | NP_788829.1 |
| Aminoacid Length | 189 |
| Molecular Weight | 21589 |
| FASTA Sequence | Download |
| Gene Name | NDUFB5 |
| Gene ID | 338061 |
| Protein Existence Status | Reviewed |
Secondary Information | |
| Protein Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Significance in milk | probablybregulate milk fat synthesis in bovine primary mammary epithelial cells (BMECs) |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | NA |
| CATH | Matched CATH superfamily n/a |
| Predicted Disorder Regions | 1-15, 179-189 |
| DisProt Annotation | |
| TM Helix Prediction | 1TMH; (70-92) |
| PDB ID | 5LC5,5LDW,5LDX,5O31, |
| Bibliography | Walker, J. E., Arizmendi, J. M., Dupuis, A., Fearnley, I. M., Finel, M., Medd, S. M., Pilkington, S. J., Runswick, M. J., & Skehel, J. M. (1992). Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction. Journal of molecular biology, 226(4), 1051–1072. https://doi.org/10.1016/0022-2836(92)91052-q |