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Primary Information | |
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| BoMiProt ID | Bomi7365 |
| Protein Name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7/Complex I-B14.5a/NADH-ubiquinone oxidoreductase subunit B14.5a |
| Organism | Bos taurus |
| Uniprot ID | Q05752 |
| Milk Fraction | Whey,MFGM |
| Ref Sequence ID | NP_788831.1 |
| Aminoacid Length | 113 |
| Molecular Weight | 12677 |
| FASTA Sequence | Download |
| Gene Name | NDUFA7/CI-B14-5A |
| Gene ID | 338063 |
| Protein Existence Status | reviewed |
Secondary Information | |
| Protein Function | a subunit of a multiprotein complex NADH dehydrogenase(ubiquinone) 1 located in the inner mitochondrial membrane. the transfer of electrons from NADH to the respiratory chain. |
| Biochemical Properties | 113 aa long.12.5kd Protein.N terminal has hydrophobic domain.C terminal has hydrophilic domain. |
| PTMs | phosphorylation and acetylation |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | NA |
| CATH | Matched CATH superfamily n/a |
| Predicted Disorder Regions | 1-10, 22-113 |
| DisProt Annotation | |
| TM Helix Prediction | no TM helices |
| Significance of PTMs | Bovine heart complex 1 - B14.5a subunit are found to be serine phosphorylated.Both B14.5a and B14.5b subunits of complex I are Nacetylated.might have an impact on its conformation and activity. |
| PDB ID | 5O31, |
| Bibliography | Palmisano G, Sardanelli AM, Signorile A, Papa S, Larsen MR. The phosphorylation pattern of bovine heart complex I subunits. Proteomics. 2007 May;7(10):1575-83. doi: 10.1002/pmic.200600801. PMID: 17443843. |