Search by BoMiProt ID - Bomi7323

Primary Information

BoMiProt ID Bomi7323
Protein Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 2/Dimethylargininase-2/DDAHII
Organism Bos taurus
Uniprot IDQ3SX44
Milk FractionWhey
Ref Sequence ID NP_001029876.1
Aminoacid Length 285
Molecular Weight 29780
FASTA Sequence Download
Gene Name DDAH2
Gene ID 540386
Protein Existence Status reviewed

Secondary Information

Protein Function It regultes nitric oxide metabolism by Hydrolyzing N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA).
Biochemical Properties H2O + Nω,Nω-dimethyl-L-arginine = dimethylamine + L-citrulline
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions (2-11), (26-32), (92-96), (233-241)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Zhou, Q., Chen, S., Li, H., Yang, B., Chen, T., Hu, T., Yin, D., He, H., & He, M. (2020). Tetramethylpyrazine alleviates iron overload damage in vascular endothelium via upregulating DDAHII expression. Toxicology in vitro : an international journal published in association with BIBRA, 65, 104817.