Primary Information |
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| BoMiProt ID | Bomi7202 |
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| Protein Name | MOB kinase activator 3B/Mob1 homolog 2b/Mps one binder kinase activator-like 2B |
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| Organism | Bos taurus |
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| Uniprot ID | Q29RK9 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001039956.1 |
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| Aminoacid Length | 216 |
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| Molecular Weight | 25450 |
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| FASTA Sequence |
Download |
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| Gene Name | MOB3B |
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| Gene ID | 540817 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | pons |
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| Protein Function | MOB proteins are integral components of signaling pathways controlling important cellular processes, such as mitotic exit, centrosome duplication, apoptosis, and cell proliferation in eukaryotes. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | (1-34) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | overexpression of hMOB3 proteins did not significantly affect centrosome duplication, a known function of NDR1/2 kinases |
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| Bibliography | 1.Kohler RS, Schmitz D, Cornils H, Hemmings BA, Hergovich A. Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. Mol Cell Biol. 2010 Sep;30(18):4507-20. doi: 10.1128/MCB.00150-10. Epub 2010 Jul 12. PMID: 20624913; PMCID: PMC2937529. |
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