Primary Information |
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| BoMiProt ID | Bomi7146 |
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| Protein Name | Mitochondrial import inner membrane translocase subunit Tim23 |
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| Organism | Bos taurus |
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| Uniprot ID | A4IFL0 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001077127.1 |
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| Aminoacid Length | 209 |
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| Molecular Weight | 21827 |
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| FASTA Sequence |
Download |
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| Gene Name | TIMM23 |
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| Gene ID | 509841 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.The import motor of the mitochondrial (mt)TIM23 complex drives translocation of presequence-containing preproteins across the mitochondrial inner membrane in an ATP-dependent manner. |
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| Biochemical Properties | The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2 |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 2 disordered segments; (1-26), (207-209) |
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| DisProt Annotation | |
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| TM Helix Prediction | 3TMHs; (75-93), (123-145), (176-194) |
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| Bibliography | Mokranjac D, Sichting M, Popov-Celeketić D, Berg A, Hell K, Neupert W. The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2. J Biol Chem. 2005 Sep 9;280(36):31608-14. doi: 10.1074/jbc.M502397200. Epub 2005 Jul 18. PMID: 16027163. |
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