Primary Information
BoMiProt ID	Bomi7133
Protein Name	Mitochondrial 2-oxodicarboxylate carrier
Organism	Bos taurus
Uniprot ID	A0JN87
Milk Fraction	Whey
Ref Sequence ID	XP_005222099.1
Aminoacid Length	299
Molecular Weight	33108
FASTA Sequence	Download
Gene Name	SLC25A21
Gene ID	513423
Protein Existence Status	reviewed
Secondary Information
Protein Function	SLC25A21 transports 2-oxoadipate and 2-oxoglutarate across the inner membrane of mitochondria by a counterexchange mechanism
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	1 disordered segment; (1-12)
DisProt Annotation
TM Helix Prediction	No TM helices
Additional Comments	Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy–like disease
Bibliography	Boczonadi V, King MS, Smith AC, Olahova M, Bansagi B, Roos A, Eyassu F, Borchers C, Ramesh V, Lochmüller H, Polvikoski T, Whittaker RG, Pyle A, Griffin H, Taylor RW, Chinnery PF, Robinson AJ, Kunji ERS, Horvath R. Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease. Genet Med. 2018 Oct;20(10):1224-1235. doi: 10.1038/gim.2017.251. Epub 2018 Mar 8. Erratum in: Genet Med. 2019 Sep;21(9):2163-2164. PMID: 29517768; PMCID: PMC6004311.