Primary Information |
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| BoMiProt ID | Bomi7043 |
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| Protein Name | Methenyltetrahydrofolate synthase domain-containing protein |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KI24 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001039507.1 |
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| Aminoacid Length | 380 |
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| Molecular Weight | 41483 |
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| FASTA Sequence |
Download |
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| Gene Name | MTHFSD |
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| Gene ID | 509897 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | RNA binding proteins.MTHFSD is a component of stress granules induced by oxidative stress |
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| Biochemical Properties | contains a RRM domain, common among ALS-related proteins and components of stress granules |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 250-257, 269-281, 358-380 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain. 2016 Jan;139(Pt 1):86-100. doi: 10.1093/brain/awv308. Epub 2015 Nov 2. PMID: 26525917. |
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