Primary Information |
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| BoMiProt ID | Bomi6952 |
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| Protein Name | Mannose-6-phosphate isomerase/Phosphohexomutase/Phosphomannose isomerase |
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| Organism | Bos taurus |
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| Uniprot ID | Q3SZI0 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001030361.1 |
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| Aminoacid Length | 423 |
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| Molecular Weight | 46369 |
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| FASTA Sequence |
Download |
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| Gene Name | MPI |
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| Gene ID | 513586 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | PMI expression acts as a potential biomarker to predict the prognosis of PDAC. |
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| PTMs | Phosphorylation at Ser,N-acetylation at Ala |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q3SZI0|MPI_BOVIN Mannose-6-phosphate isomerase OS=Bos taurus OX=9913 GN=MPI PE=2 SV=3
MAAQRVFPLSCVVQQYAWGKMGSNSEVARLLASSDPLAQISEDRPYAELWMGTHPRGDAK
ILDNRISQKTLGQWIADNQDSLGSKVKDTFNGKLPFLFKVLS*102VETALS*108IQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLTKVPEFQFLIGDNAAAQLK
QSLSQDSEAVTSALRSCFSHLMKSEKKVVVEQLNLLVKRISQQVAAGNNMEDICGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSPSQDRLFPPARSPEDPYLSIYDPPVPDFTVMKVEVPGSVTEYK
VLALDSASILLVVQGTVTASSPTAQAAIPLKRGGVLFIGANESVSLKLTVPKDLLMFRAC
CLL
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Alipour Z, Agostini-Vulaj D, Findeis-Hosey J, Liu L, Gonzalez RS, Drage MG, Krigman H, Zhou Z. Phosphomannose Isomerase High Expression Associated with Better Prognosis in Pancreatic Ductal Adenocarcinoma. Clin Exp Gastroenterol. 2021 Sep 1;14:353-360. doi: 10.2147/CEG.S316492. PMID: 34511962; PMCID: PMC8421669. |
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