Primary Information |
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| BoMiProt ID | Bomi6937 |
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| Protein Name | Major facilitator superfamily domain-containing protein 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q1JQC1 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001068819.1 |
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| Aminoacid Length | 468 |
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| Molecular Weight | 51538 |
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| FASTA Sequence |
Download |
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| Gene Name | MFSD1 |
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| Gene ID | 508337 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | Lysosomal transporter which is essential for liver homeostasis. Required to maintain stability and lysosomal localization of GLMP. |
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| PTMs | Phosphorylation and Ubl conjugation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 1-34, 461-468 |
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| DisProt Annotation | |
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| TM Helix Prediction | 11 TMHs ; (45-63), (84-106), (115-137), (175-197), (216-238), (268-290), (305-327), (334-356), (360-382), (389-411) and (420-442) |
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| Bibliography | Perland, E., Hellsten, S. V., Lekholm, E., Eriksson, M. M., Arapi, V., & Fredriksson, R. (2017). The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. Journal of molecular neuroscience : MN, 61(2), 199–214. https://doi.org/10.1007/s12031-016-0867-8 |
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