Primary Information |
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BoMiProt ID | Bomi6914 |
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Protein Name | Lysozyme-like protein 1 |
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Organism | Bos taurus |
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Uniprot ID | A0JNM6 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_001071378.1 |
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Aminoacid Length | 148 |
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Molecular Weight | 16779 |
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FASTA Sequence |
Download |
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Gene Name | LYZL1 |
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Gene ID | 512087 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | lysozyme activity.antibacterial action of LYZL1 is involved bacterial membrane damage and leakage of cellular contents.role in male reproductive tract innate immunity. |
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Biochemical Properties | presence of α-helix, β-sheet and random coil with α-helix .possess peptidoglycan binding ability.Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.The catalytic mechanism ofmlysozymes involves the interaction of Glu35 and Asp52 of the active site with beta-1,4 glycosidic bond of the substrate. |
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PTMs | Glycosylation and Disulfide bond addition |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|A0JNM6|LYZL1_BOVIN Lysozyme-like protein 1 OS=Bos taurus OX=9913 GN=LYZL1 PE=2 SV=1
MKAAGILALMGCLVTVVEPKVYTRCKLAKIFSRASLDNYRGFSLGNWICMAYYESHYN*58TT
AQTQLEDGSTDYGIFQINSDTWCRSTKLQEKNRCHVACSALMTDDLTDAIICAKKIVKET
DGMNYWQGWKKNCEGRDLSEWKKGCEVS
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Predicted Disorder Regions | NA |
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DisProt Annotation | |
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TM Helix Prediction | no TM helices |
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Bibliography | Narmadha G, Yenugu S. In Silico and Biochemical Characterization of Lysozyme-Like Proteins in the Rat. PLoS One. 2016 Sep 9;11(9):e0161909. doi: 10.1371/journal.pone.0161909. PMID: 27611690; PMCID: PMC5017655. |