Primary Information
BoMiProt ID	Bomi6702
Protein Name	Lambda-crystallin homolog/L-gulonate 3-dehydrogenase/Gul3DH
Organism	Bos taurus
Uniprot ID	Q8SPX7
Milk Fraction	Whey
Ref Sequence ID	NP_776718.1
Aminoacid Length	321
Molecular Weight	35072
FASTA Sequence	Download
Gene Name	CRYL1
Gene ID	281725
Protein Existence Status	reviewed
Secondary Information
Protein Function	composition of lens
Biochemical Properties	It catalyses conversion of L-gulonate to 3-dehydro-L-gulonate by utilising a NAD+ and reducing it to NADH.
PTMs	Phosphorylation on Ser
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q8SPX7|CRYL1_BOVIN Lambda-crystallin homolog OS=Bos taurus OX=9913 GN=CRYL1 PE=2 SV=3 MASPGS*6SAPGGVAVVGSGLIGRSWAMLFASAGFRVKLFDIEPRQVTDALVSLRKEMKMLE LSGYLKGELGAEEQLSLISGCSDLREAVEGALHVQECVPENLELKRKLFAQLDKIADDHV ILSSSSSCLLPSKLFAGLAHVKQCLVAHPVNPPYYVPLVELVPHPETAPATVDRTYALMR RVGQSPVRLLREIDGFALNRLQYAVIAEAWRLVEEGVVSPGDLDLVMSDGLGLRYAFIGP LETMHLNAEGMLSYCDRYGEGMKRVLKTFGPVPEFSGATAEKVHQAMCVKVPDDAEHLAA RRAWRDGCLMRLAQLKHQLPQ
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Chen, J., Yu, L., Li, D., Gao, Q., Wang, J., Huang, X., Bi, G., Wu, H., & Zhao, S. (2003). Human CRYL1, a novel enzyme-crystallin overexpressed in liver and kidney and downregulated in 58% of liver cancer tissues from 60 Chinese patients, and four new homologs from other mammalians. Gene, 302(1-2), 103–113. https://doi.org/10.1016/s0378-1119(02)01095-8