Primary Information
BoMiProt ID	Bomi6685
Protein Name	Krev interaction trapped protein 1/Cerebral cavernous malformations 1 protein homolog
Organism	Bos taurus
Uniprot ID	Q6TNJ1
Milk Fraction	Exosomes
Ref Sequence ID	NP_001001166.1
Aminoacid Length	736
Molecular Weight	84291
FASTA Sequence	Download
Gene Name	KRIT1
Gene ID	407996
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Krev interaction-trapped 1 (KRIT1), an adherens junction accessory protein required for cell-cell junction stability, in regulating these vascular functions.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Corr M, Lerman I, Keubel JM, Ronacher L, Misra R, Lund F, Sarelius IH, Glading AJ. Decreased Krev interaction-trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo. Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2702-10. doi: 10.1161/ATVBAHA.112.300115. Epub 2012 Aug 23. PMID: 22922958; PMCID: PMC3475761.