Primary Information |
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| BoMiProt ID | Bomi6557 |
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| Protein Name | Junctional protein associated with coronary artery disease homolog |
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| Organism | Bos taurus |
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| Uniprot ID | A2VE02 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001075943.1 |
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| Aminoacid Length | 1305 |
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| Molecular Weight | 140176 |
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| FASTA Sequence |
Download |
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| Gene Name | JCAD |
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| Gene ID | 784675 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | endothelial, cell-cell junction protein.cell adhesion.positive regulation of vascular endothelial growth factor signaling pathway. |
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| PTMs | phosphorylation on Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|A2VE02|JCAD_BOVIN Junctional protein associated with coronary artery disease homolog OS=Bos taurus OX=9913 GN=JCAD PE=2 SV=1
MYSVEDLLISHGYKLSRKLPAPHEDDGERRQPARTTVPAGPGLLNGCDDGPAALPRGKAS
PGTGLLSDPESRRLGPRGHGERPSTAAAARISEAGFYHQPVLAWSSQPLTGRSHAYWRRR
EQEAREDPGGRGPVPSLPTHPREGPWEVGGRSEHVMKKAVWEDELGMAGPARWQDVSVRS
WNQPPRLGRQMSDGVGEKLFQDLYPFMLGEHGLTSQSKGKSQSLPRVLSPESLSCMEVPI
PLSDGHLPGVPKVPLQPPNCASNLESTRNPKKAGTSAPLPQPRFGRPLKPPSYGSQPHSK
AGAENGSYTDSRQLDPGAAHSARTNSARQDLYGPDPGLEPPVYVPPPSYKSPPQPAAHPC
PEEAVSRHEGRGRRVPQHPMERPAAGGQPLSGSRGAGSEWGASPCSPVGVPPQPHHTTAY
DGSILIIPFDDPRIRHIKLPRPHGFWEDVKLDGAVPAPDPRSLQQEGAVWGPSGKERGPA
PADPSPSWLWGQPPRNGENGSSPDQRDPCIVTQRKQPDVSGSPQEYPESLVSSPSPQGES
SCEMQTQLRKFEAGLQPKRSSKKKTSETIFCLVSIPVKSESQLPGTDTNNNDLKQSASLQ
EQSVLSLSSTDLELQALTGSMATRTELPRPDPGGPGRGRQADDLRFPSPAKHRALAWPGP
WPGHHFRDQQTQTSFAHEPQSLQPLPGERPGGSPDPVLPPRCLDPAPFEVQMHMALASSD
PNQRPGAHSPKSQGSLSPSSNSAFSGSSWPRNQGPVPRASLGQQGSDGPGRRASPVSRGE
VIKGETTGPCNSRQLFGQFLLKPVSRRPWDLISQLESFNKELQEEEGSSGSSSDGSGSED
S*841DTELPWGSCARPAPQLPGLLKDIVPEDPRTRPGRVKSKSESWSEEGRPRSPRPWQAEGR
GSVWLSPPGSWIAEDGDREVEDRVAQLAVSPRPVKRAISSGLNDAKPEPPPDPAEQREPL
PSQELPGSRGAVELSAAGPPRAGGGEQGSTRAPLSLAGKSRGLS*1004APDLRS*1010VGLTLVQEHS
TSQLAGSPGDANAIEIPPNESLEARAARILGIEVAVESLLPGAQRAGQRRHPEPDGSALR
PESPRQEAAASLAQPNESTAPADAFYGRRKCGWTKSPLFVGERDSTRQVPRASEPADVDG
AVPTKAPETPPS*1152PLESQPFLPKDVETKPPFRSTLFHFIERTPNLAFSEKKLRNTSRVIES
LQEKLVSPPRKADPDRLTRMKEVSSVSRMRLLTSRAADS*1239AEEPKAERGPGAWLGGLVAPS
AGHKLSDPQGALSLEADGHPAARRENGGRDFWCPDSYDPSRVERV
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Shigeoka M, Arimoto S, Akashi M. JCAD expression and localization in human blood endothelial cells. Heliyon. 2020 Oct 8;6(10):e05121. doi: 10.1016/j.heliyon.2020.e05121. PMID: 33083606; PMCID: PMC7550929. |
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