Primary Information
BoMiProt ID	Bomi6439
Protein Name	Integrin beta-5
Organism	Bos taurus
Uniprot ID	P80747
Milk Fraction	Whey
Aminoacid Length	800
Molecular Weight	88057
FASTA Sequence	Download
Gene Name	ITGB5
Protein Existence Status	reviewed
Secondary Information
Presence in other biological fluids/tissue/cells	Endothelial cells
Protein Function	cell to ECM attachment.binds to fibronectin at RGD sequence
PTMs	phosphorylation on Ser
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|P80747|ITB5_BOVIN Integrin beta-5 OS=Bos taurus OX=9913 GN=ITGB5 PE=1 SV=2 MPRAPALLFSCLLGLCALVPRLPGLNICTSGSATSCEECLLIHPKCAWCFKEDFGSLRSV TSRCDLKANLIRNGCGVEFESPASSTQVLRSLPLSSKGSSPAGSDVIQLTPQEVTVTLRP GDRTAFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFG SFVDKNISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVS RNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQC HLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKN*347FTALIPGTTVEIL HGDSKNILQLIINAYNSIRSKVELSVWDQPEDLNLFFTATCQDGVSYPGQRKCEGLKIGD TASFEVSVEARSCPSKHVQHTFTLRPVGFRDSLEVGVTYNCRCGCSAGLEPDSARCSSN*479G TYVCGLCECNPGYLGTRCECQEGESQSGYQNLCREAEGKPLCSGRGQCSCNQCSCFESEF GKIYGSFCECDN*552FSCARNKGVLCSGHGECHCGECKCHAGYIGDNCN*586CSTDISTCQARDGH ICSDRGHCVCGQCQCTEPGAFGETCEKCPTCPDACSTKRDCVECLLLHSGSSADN*655QTCQN LCKDEVITRVDTIVKDDQEAVLCFYKTAKDCVMMFTYSELPSGKSN*706LTVLREPECGTAPS AMTILLAVVGSILLTGFALLVIWKLLVTIHDRREFAKFQSERSRARYEMAS*771NPLYRKPIS THTVDFTFNKFNKSYNGTVD
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	1TMH; (721-743)
Bibliography	Zhang LY, Guo Q, Guan GF, Cheng W, Cheng P, Wu AH. Integrin Beta 5 Is a Prognostic Biomarker and Potential Therapeutic Target in Glioblastoma. Front Oncol. 2019 Sep 20;9:904. doi: 10.3389/fonc.2019.00904. PMID: 31616629; PMCID: PMC6764112.