Primary Information
BoMiProt ID	Bomi6420
Protein Name	Integrator complex subunit 12/Int12/PHD finger protein 22
Organism	Bos taurus
Uniprot ID	Q32LL5
Milk Fraction	Whey
Ref Sequence ID	NP_001069221.1
Aminoacid Length	462
Molecular Weight	48557
FASTA Sequence	Download
Gene Name	INTS12/PHF22
Gene ID	517489
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q32LL5|INT12_BOVIN Integrator complex subunit 12 OS=Bos taurus OX=9913 GN=INTS12 PE=2 SV=1 MAAAVNLELDPIFLKALGFLHSKSKDSAEKLKTLLDESLARGIDSSYRPSQKDVEPPKIS STKTVSVKQEPKTSSSLPSGNNNGKVLTTEKVKKEGEKRPADKMKSDITEGADVPKKPRL EKPETRSS*128PITVQTSKDLAMADLSSFEETSADDFAMEMGLACVVCRQMTVASGNQLVECQ ECHNLYHQDCHKPQVTDKEVTDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPTVVSVAPA VKDPLVKKPETKLKPETTFLAFKRSEVKASTVVSGNSSSTNVSSSATSGLIGWAAFAAKT TSAGPSTAKLSSAAQNNSGKPATSSANQKPVGLTGLATTSKGGIGSKIGSSNSTSPTVPL KPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTNKT ASEPSTSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
Predicted Disorder Regions	21-131, 148-154, 218-256, 269-358, 369-462
DisProt Annotation
TM Helix Prediction	no TM helices
Bibliography	Obeidat, M., Miller, S., Probert, K., Billington, C. K., Henry, A. P., Hodge, E., Nelson, C. P., Stewart, C. E., Swan, C., Wain, L. V., Soler Artigas, M., Melén, E., Ushey, K., Hao, K., Lamontagne, M., Bossé, Y., Postma, D. S., Tobin, M. D., Sayers, I., & Hall, I. P. (2013). GSTCD and INTS12 regulation and expression in the human lung. PloS one, 8(9), e74630. https://doi.org/10.1371/journal.pone.0074630